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Target protein-oriented isolation of Hes1 dimer inhibitors using protein based methods
Natural products isolation using protein based methods is an attractive for obtaining bioactive compounds. To discover neural stem cell (NSC) differentiation activators, we isolated eight inhibitors of Hes1 dimer formation from Psidium guajava using the Hes1-Hes1 interaction fluorescent plate assay...
Shranjeno v:
| izdano v: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6987128/ https://ncbi.nlm.nih.gov/pubmed/31992824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58451-3 |
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