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Optimization of the Lipase-Catalyzed Selective Amidation of Phenylglycinol

Ceramides and their analogs have a regulatory effect on inflammatory cytokines expression. It was found that a kind of ceramides analog synthesized from phenylglycinol could inhibit the production of cytokine TNF-α. However, two active hydrogen groups are present in the phenylglycinol molecule. It i...

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Pubblicato in:Front Bioeng Biotechnol
Autori principali: Sun, Meina, Nie, Kaili, Wang, Fang, Deng, Li
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6987038/
https://ncbi.nlm.nih.gov/pubmed/32039186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00486
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