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A one‐pot process for synthesis of mitomycin analogs catalyzed by laccase/lipase optimized by response surface methodology

To reach the excellent yield as well as environmental friendliness, an efficient one‐pot process for the synthesis of 2‐methyl‐3‐n‐butylaminoyl‐1,4‐benzoquinone, a mitomycin‐like compound by the domino reaction of 2‐methyl‐1,4‐hydroquinone and butylamine using laccase/lipase as co‐catalysts, has bee...

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Detalhes bibliográficos
Publicado no:Eng Life Sci
Main Authors: Zhang, Yuanyuan, Yao, Quancai, Li, Zewen, Yang, Fengke, Wang, Fanye, Liu, Junhong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6999360/
https://ncbi.nlm.nih.gov/pubmed/32624973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elsc.201900118
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