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Selective Formation of Secondary Amides via the Copper-Catalyzed Cross-Coupling of Alkylboronic Acids with Primary Amides

[Image: see text] For the first time, a general catalytic procedure for the cross coupling of primary amides and alkylboronic acids is demonstrated. The key to the success of this reaction was the identification of a mild base (NaOSiMe(3)) and oxidant (di-tert-butyl peroxide) to promote the copper-c...

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Bibliografiske detaljer
Udgivet i:Org Lett
Main Authors: Rossi, Steven A., Shimkin, Kirk W., Xu, Qun, Mori-Quiroz, Luis M., Watson, Donald A.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265364/
https://ncbi.nlm.nih.gov/pubmed/23611591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol401004r
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