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Selective Formation of Secondary Amides via the Copper-Catalyzed Cross-Coupling of Alkylboronic Acids with Primary Amides
[Image: see text] For the first time, a general catalytic procedure for the cross coupling of primary amides and alkylboronic acids is demonstrated. The key to the success of this reaction was the identification of a mild base (NaOSiMe(3)) and oxidant (di-tert-butyl peroxide) to promote the copper-c...
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| Pubblicato in: | Org Lett |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4265364/ https://ncbi.nlm.nih.gov/pubmed/23611591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol401004r |
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