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Delta-like 1 and Delta-like 4 differently require their extracellular domains for triggering Notch signaling in mice

Delta-like (Dll) 1 and Dll4 differently function as Notch ligands in a context-dependent manner. As these ligands share structural properties, the molecular basis for their functional difference is poorly understood. Here, we investigated the superiority of Dll4 over Dll1 with respect to induction o...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:eLife
Main Authors: Hirano, Ken-ichi, Suganami, Akiko, Tamura, Yutaka, Yagita, Hideo, Habu, Sonoko, Kitagawa, Motoo, Sato, Takehito, Hozumi, Katsuto
פורמט: Artigo
שפה:Inglês
יצא לאור: eLife Sciences Publications, Ltd 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986876/
https://ncbi.nlm.nih.gov/pubmed/31934853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50979
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