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Delta-like 1 and Delta-like 4 differently require their extracellular domains for triggering Notch signaling in mice

Delta-like (Dll) 1 and Dll4 differently function as Notch ligands in a context-dependent manner. As these ligands share structural properties, the molecular basis for their functional difference is poorly understood. Here, we investigated the superiority of Dll4 over Dll1 with respect to induction o...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Hirano, Ken-ichi, Suganami, Akiko, Tamura, Yutaka, Yagita, Hideo, Habu, Sonoko, Kitagawa, Motoo, Sato, Takehito, Hozumi, Katsuto
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6986876/
https://ncbi.nlm.nih.gov/pubmed/31934853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.50979
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