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Current strategies towards therapeutic manipulation of mtDNA heteroplasmy
Mitochondrial disease is a multifactorial disorder involving both nuclear and mitochondrial genomes. Over the past 20 years, great progress was achieved in the field of gene editing which raised the possibility of partial or complete elimination of mutant mtDNA that causes disease phenotypes. Each c...
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| Publicat a: | Front Biosci (Landmark Ed) |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6986768/ https://ncbi.nlm.nih.gov/pubmed/27814659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2741/4529 |
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