Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy

mtDNA is present in multiple copies in each cell derived from the expansions of those in the oocyte. Heteroplasmy, more than one mtDNA variant, may be generated by mutagenesis, paternal mtDNA leakage, and novel medical technologies aiming to prevent inheritance of mtDNA-linked diseases. Heteroplasmy...

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Bibliografiska uppgifter
I publikationen:Cell Metab
Huvudupphovsmän: Latorre-Pellicer, Ana, Lechuga-Vieco, Ana Victoria, Johnston, Iain G., Hämäläinen, Riikka H., Pellico, Juan, Justo-Méndez, Raquel, Fernández-Toro, Jose María, Clavería, Cristina, Guaras, Adela, Sierra, Rocío, Llop, Jordi, Torres, Miguel, Criado, Luis Miguel, Suomalainen, Anu, Jones, Nick S., Ruíz-Cabello, Jesús, Enríquez, José Antonio
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cell Press 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899444/
https://ncbi.nlm.nih.gov/pubmed/31588014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.09.007
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