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Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy

mtDNA is present in multiple copies in each cell derived from the expansions of those in the oocyte. Heteroplasmy, more than one mtDNA variant, may be generated by mutagenesis, paternal mtDNA leakage, and novel medical technologies aiming to prevent inheritance of mtDNA-linked diseases. Heteroplasmy...

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Dades bibliogràfiques
Publicat a:Cell Metab
Autors principals: Latorre-Pellicer, Ana, Lechuga-Vieco, Ana Victoria, Johnston, Iain G., Hämäläinen, Riikka H., Pellico, Juan, Justo-Méndez, Raquel, Fernández-Toro, Jose María, Clavería, Cristina, Guaras, Adela, Sierra, Rocío, Llop, Jordi, Torres, Miguel, Criado, Luis Miguel, Suomalainen, Anu, Jones, Nick S., Ruíz-Cabello, Jesús, Enríquez, José Antonio
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6899444/
https://ncbi.nlm.nih.gov/pubmed/31588014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.09.007
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