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Regulation of Mother-to-Offspring Transmission of mtDNA Heteroplasmy
mtDNA is present in multiple copies in each cell derived from the expansions of those in the oocyte. Heteroplasmy, more than one mtDNA variant, may be generated by mutagenesis, paternal mtDNA leakage, and novel medical technologies aiming to prevent inheritance of mtDNA-linked diseases. Heteroplasmy...
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| Published in: | Cell Metab |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Cell Press
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6899444/ https://ncbi.nlm.nih.gov/pubmed/31588014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.09.007 |
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