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FocAn: automated 3D analysis of DNA repair foci in image stacks acquired by confocal fluorescence microscopy
BACKGROUND: Phosphorylated histone H2AX, also known as γH2AX, forms μm-sized nuclear foci at the sites of DNA double-strand breaks (DSBs) induced by ionizing radiation and other agents. Due to their specificity and sensitivity, γH2AX immunoassays have become the gold standard for studying DSB induct...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | BMC Bioinformatics |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6986076/ https://ncbi.nlm.nih.gov/pubmed/31992200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-3370-8 |
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