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TAK1 deficiency attenuates cisplatin-induced acute kidney injury

Cisplatin can cause acute kidney injury (AKI), but the molecular mechanisms are not well understood. The objective of the present study was to examine the role of transforming growth factor-β-activated kinase-1 (TAK1) in the pathogenesis of cisplatin-induced AKI. Wild-type mice and proximal tubule T...

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Vydáno v:Am J Physiol Renal Physiol
Hlavní autoři: Zhou, Jun, An, Changlong, Jin, Xiaogao, Hu, Zhaoyong, Safirstein, Robert L., Wang, Yanlin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985823/
https://ncbi.nlm.nih.gov/pubmed/31813254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00516.2019
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