AMP-activated protein kinase contributes to cisplatin-induced renal epithelial cell apoptosis and acute kidney injury

Cisplatin, a commonly used anticancer drug, has been shown to induce acute kidney injury, which limits its clinical use in cancer treatment. Emerging evidence has suggested that AMP-activated protein kinase (AMPK), which functions as a cellular energy sensor, is activated by various cellular stresse...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Jin, Xiaogao, An, Changlong, Jiao, Baihai, Safirstein, Robert L., Wang, Yanlin
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792694/
https://ncbi.nlm.nih.gov/pubmed/33103444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00354.2020
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