TCR(+)CD4(−)CD8(−) (double negative) T cells protect from cisplatin-induced renal epithelial cell apoptosis and acute kidney injury

Acute kidney injury (AKI) due to cisplatin is a significant problem that limits its use as an effective chemotherapeutic agent. T cell receptor(+)CD4(−)CD8(−) double negative (DN) T cells constitute the major T cell population in the human and mouse kidney, express programmed cell death protein (PD)...

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Publicat a:Am J Physiol Renal Physiol
Autors principals: Gong, Jing, Noel, Sanjeev, Hsu, Joshua, Bush, Errol L., Arend, Lois J., Sadasivam, Mohanraj, Lee, Sul A, Kurzhagen, Johanna T., Hamad, Abdel Rahim A., Rabb, Hamid
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7311707/
https://ncbi.nlm.nih.gov/pubmed/32281417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00033.2020
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