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Regulation of NKCC2B by TNF-α in response to salt restriction

We have previously shown that TNF-α produced by renal epithelial cells inhibits Na(+)-K(+)-2Cl(−) cotransporter (NKCC2) activity as part of a mechanism that attenuates increases in blood pressure in response to high NaCl intake. As the role of TNF-α in the kidney is still being defined, the effects...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Hao, Shoujin, Salzo, Joseph, Hao, Mary, Ferreri, Nicholas R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985818/
https://ncbi.nlm.nih.gov/pubmed/31813248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00388.2019
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