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Systemic Safety of a Recombinant AAV8 Vector for Human Cocaine Hydrolase Gene Therapy: A Good Laboratory Practice Preclinical Study in Mice

Cocaine addiction continues to impose major burdens on affected individuals and broader society but is highly resistant to medical treatment or psychotherapy. This study was undertaken with the goal of Food and Drug Administration (FDA) permission for a first-in-human clinical trial of a gene therap...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Chen, Vicky Ping, Gao, Yang, Geng, Liyi, Steele, Mike, Jenks, Nathan, Peng, Kah-Whye, Brimijoin, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6985763/
https://ncbi.nlm.nih.gov/pubmed/31650869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2019.233
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