Effects of anti-cocaine vaccine and viral gene transfer of cocaine hydrolase in mice on cocaine toxicity including motor strength and liver damage

In developing an vivo drug-interception therapy to treat cocaine abuse and hinder relapse into drug seeking provoked by re-encounter with cocaine, two promising agents are: 1) a cocaine hydrolase enzyme (CocH) derived from human butyrylcholinesterase and delivered by gene transfer: 2) an anti-cocain...

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Bibliographic Details
Main Authors: Gao, Yang, Geng, Liyi, Orson, Frank, Kinsey, Berma, Kosten, Thomas R, Shen, Xiaoyun, Brimijoin, Stephen
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537841/
https://ncbi.nlm.nih.gov/pubmed/22935511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2012.08.006
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