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Constitutive CD8 expression drives innate CD8(+) T-cell differentiation via induction of iNKT2 cells
Temporal down-regulation of the CD8 co-receptor after receiving positive-selection signals has been proposed to serve as an important determinant to segregate helper versus cytotoxic lineages by generating differences in the duration of TCR signaling between MHC-I and MHC-II selected thymocytes. By...
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| Publicado no: | Life Sci Alliance |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Life Science Alliance LLC
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6985454/ https://ncbi.nlm.nih.gov/pubmed/31980555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000642 |
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