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Quantitative Difference in PLZF Protein Expression Determines iNKT Lineage Fate and Controls Innate CD8 T Cell Generation

Zbtb16 encodes the zinc-finger protein PLZF, which is often used as a lineage marker for innate-like T cells and is specifically required for the generation of invariant natural killer T (iNKT) cells in the thymus. Here, we report that not only PLZF expression itself but also the relative abundance...

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Dettagli Bibliografici
Pubblicato in:Cell Rep
Autori principali: Park, Joo-Young, DiPalma, Devon T., Kwon, Juntae, Fink, Juliet, Park, Jung-Hyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274958/
https://ncbi.nlm.nih.gov/pubmed/31141681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.05.012
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