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Modeling Polyglutamine Expansion Diseases with Induced Pluripotent Stem Cells
Polyglutamine expansion disorders, which include Huntington’s disease, have expanded CAG repeats that result in polyglutamine expansions in affected proteins. How this specific feature leads to distinct neuropathies in 11 different diseases is a fascinating area of investigation. Most proteins affec...
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| Publicado no: | Neurotherapeutics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6985408/ https://ncbi.nlm.nih.gov/pubmed/31792895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-019-00810-8 |
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