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Characterization of Human Huntington's Disease Cell Model from Induced Pluripotent Stem Cells
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disease caused by a CAG repeat expansion in the first exon of the gene Huntingtin (Htt). A dramatic pathological change in HD is the massive loss of striatal neurons as the disease progresses. A useful advance in HD would be the g...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966296/ https://ncbi.nlm.nih.gov/pubmed/21037797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1193 |
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