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Modeling Huntington’s Disease with Induced Pluripotent Stem Cells
Huntington’s disease (HD) causes severe motor dysfunction, behavioral abnormalities, cognitive impairment and death. Investigations into its molecular pathology have primarily relied on murine tissues; however, the recent discovery of induced pluripotent stem cells (iPSCs) has opened new possibiliti...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791169/ https://ncbi.nlm.nih.gov/pubmed/23459227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2013.02.005 |
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