Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma

GBM (glioblastoma multiforme) is the most common and aggressive brain tumor with no curative options available. Therefore, it is imperative to develop novel potent therapeutic drugs for GBM treatment. Here, we show that regorafenib, an oral multi-kinase inhibitor, exhibits superior therapeutic effic...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Jiang, Jingwen, Zhang, Lu, Chen, Haining, Lei, Yunlong, Zhang, Tao, Wang, Yuelong, Jin, Ping, Lan, Jiang, Zhou, Li, Huang, Zhao, Li, Bowen, Liu, Yuan, Gao, Wei, Xie, Ke, Zhou, Liangxue, Nice, Edouard C., Peng, Yong, Cao, Yihai, Wei, Yuquan, Wang, Kui, Huang, Canhua
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984601/
https://ncbi.nlm.nih.gov/pubmed/30909789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1598752
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