Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma

GBM (glioblastoma multiforme) is the most common and aggressive brain tumor with no curative options available. Therefore, it is imperative to develop novel potent therapeutic drugs for GBM treatment. Here, we show that regorafenib, an oral multi-kinase inhibitor, exhibits superior therapeutic effic...

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Bibliografiska uppgifter
I publikationen:Autophagy
Huvudupphovsmän: Jiang, Jingwen, Zhang, Lu, Chen, Haining, Lei, Yunlong, Zhang, Tao, Wang, Yuelong, Jin, Ping, Lan, Jiang, Zhou, Li, Huang, Zhao, Li, Bowen, Liu, Yuan, Gao, Wei, Xie, Ke, Zhou, Liangxue, Nice, Edouard C., Peng, Yong, Cao, Yihai, Wei, Yuquan, Wang, Kui, Huang, Canhua
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2019
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984601/
https://ncbi.nlm.nih.gov/pubmed/30909789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1598752
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