Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma

GBM (glioblastoma multiforme) is the most common and aggressive brain tumor with no curative options available. Therefore, it is imperative to develop novel potent therapeutic drugs for GBM treatment. Here, we show that regorafenib, an oral multi-kinase inhibitor, exhibits superior therapeutic effic...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Autophagy
Päätekijät: Jiang, Jingwen, Zhang, Lu, Chen, Haining, Lei, Yunlong, Zhang, Tao, Wang, Yuelong, Jin, Ping, Lan, Jiang, Zhou, Li, Huang, Zhao, Li, Bowen, Liu, Yuan, Gao, Wei, Xie, Ke, Zhou, Liangxue, Nice, Edouard C., Peng, Yong, Cao, Yihai, Wei, Yuquan, Wang, Kui, Huang, Canhua
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2019
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984601/
https://ncbi.nlm.nih.gov/pubmed/30909789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1598752
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