Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity

Saturated fatty acid (SFA)-induced lipotoxicity is caused by the accumulation of reactive oxygen species (ROS), which is associated with damaged mitochondria. Moreover, lipotoxicity is crucial for the progression of nonalcoholic steatohepatitis (NASH). Autophagy is required for the clearance of prot...

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Publicado en:Autophagy
Autores principales: Park, Jeong Su, Lee, Da Hyun, Lee, Yu Seol, Oh, Eunji, Bae, Kwang-Hee, Oh, Kyoung-Jin, Kim, Hyunmi, Bae, Soo Han
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984596/
https://ncbi.nlm.nih.gov/pubmed/30907226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1598751
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