Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity

Saturated fatty acid (SFA)-induced lipotoxicity is caused by the accumulation of reactive oxygen species (ROS), which is associated with damaged mitochondria. Moreover, lipotoxicity is crucial for the progression of nonalcoholic steatohepatitis (NASH). Autophagy is required for the clearance of prot...

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Bibliografiske detaljer
Udgivet i:Autophagy
Main Authors: Park, Jeong Su, Lee, Da Hyun, Lee, Yu Seol, Oh, Eunji, Bae, Kwang-Hee, Oh, Kyoung-Jin, Kim, Hyunmi, Bae, Soo Han
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984596/
https://ncbi.nlm.nih.gov/pubmed/30907226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1598751
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