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Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity

Saturated fatty acid (SFA)-induced lipotoxicity is caused by the accumulation of reactive oxygen species (ROS), which is associated with damaged mitochondria. Moreover, lipotoxicity is crucial for the progression of nonalcoholic steatohepatitis (NASH). Autophagy is required for the clearance of prot...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Park, Jeong Su, Lee, Da Hyun, Lee, Yu Seol, Oh, Eunji, Bae, Kwang-Hee, Oh, Kyoung-Jin, Kim, Hyunmi, Bae, Soo Han
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984596/
https://ncbi.nlm.nih.gov/pubmed/30907226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1598751
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