Dual roles of ULK1 (unc-51 like autophagy activating kinase 1) in cytoprotection against lipotoxicity

Saturated fatty acid (SFA)-induced lipotoxicity is caused by the accumulation of reactive oxygen species (ROS), which is associated with damaged mitochondria. Moreover, lipotoxicity is crucial for the progression of nonalcoholic steatohepatitis (NASH). Autophagy is required for the clearance of prot...

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Publicat a:Autophagy
Autors principals: Park, Jeong Su, Lee, Da Hyun, Lee, Yu Seol, Oh, Eunji, Bae, Kwang-Hee, Oh, Kyoung-Jin, Kim, Hyunmi, Bae, Soo Han
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984596/
https://ncbi.nlm.nih.gov/pubmed/30907226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1598751
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