Učitavanje...

The secret life of degradative lysosomes in axons: delivery from the soma, enzymatic activity, and local autophagic clearance

Lysosomal degradation of protein aggregates and damaged organelles is essential for maintaining cellular homeostasis. This process in neurons is challenging due to their highly polarized architecture. While enzymatically active degradative lysosomes are enriched in the cell body, their trafficking a...

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Bibliografski detalji
Izdano u:Autophagy
Glavni autori: Farfel-Becker, Tamar, Roney, Joseph C., Cheng, Xiu-Tang, Li, Sunan, Cuddy, Sean R., Sheng, Zu-Hang
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984450/
https://ncbi.nlm.nih.gov/pubmed/31533518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1669869
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