A carregar...

Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A

Filamin A (FLNa), expressed in endocardial endothelia during fetal valve morphogenesis, is key in cardiac development. Missense mutations in FLNa cause non-syndromic mitral valve dysplasia (FLNAMVD). Here, we aimed to reveal the currently unknown underlying molecular mechanism behind FLNA-MVD caused...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Structure
Main Authors: Haataja, Tatu J.K., Bernardi, Rafael C., Lecointe, Simon, Capoulade, Romain, Merot, Jean, Pentikäinen, Ulla
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984350/
https://ncbi.nlm.nih.gov/pubmed/30344108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2018.09.007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!