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Skeletal Dysplasia Mutations Effect on Human Filamins’ Structure and Mechanosensing

Cells’ ability to sense mechanical cues in their environment is crucial for fundamental cellular processes, leading defects in mechanosensing to be linked to many diseases. The actin cross-linking protein Filamin has an important role in the conversion of mechanical forces into biochemical signals....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Seppälä, Jonne, Bernardi, Rafael C., Haataja, Tatu J. K., Hellman, Maarit, Pentikäinen, Olli T., Schulten, Klaus, Permi, Perttu, Ylänne, Jari, Pentikäinen, Ulla
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5484675/
https://ncbi.nlm.nih.gov/pubmed/28652603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04441-x
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