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Decrease of Cardiac Parkin Protein in Obese Mice

Mitophagy plays a major role in heart physiology. Impairment of Parkin-dependent mitophagy in heart is known to be deleterious. Obesity is a known cardiovascular risk factor. Impaired autophagy has been reported in models of obesity or hyperlipidemia/hypercholesterolemia; however less is known regar...

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Bibliographic Details
Published in:Front Cardiovasc Med
Main Authors: Thomas, Amandine, Marek-Iannucci, Stefanie, Tucker, Kyle C., Andres, Allen M., Gottlieb, Roberta A.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984192/
https://ncbi.nlm.nih.gov/pubmed/32039238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcvm.2019.00191
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