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Intermittent Use of a Short-Course Glucagon-like Peptide-1 Receptor Agonist Therapy Limits Adverse Cardiac Remodeling via Parkin-dependent Mitochondrial Turnover

Given that adverse remodeling is the leading cause of heart failure and death in the USA, there is an urgent unmet need to develop new methods in dealing with this devastating disease. Here we evaluated the efficacy of a short-course glucagon-like peptide-1 receptor agonist therapy—specifically 2-qu...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Germano, Juliana de F., Huang, Chengqun, Sin, Jon, Song, Yang, Tucker, Kyle C., Taylor, David J. R., Saadaeijahromi, Hannaneh, Stotland, Aleksandr, Piplani, Honit, Gottlieb, Roberta A., Mentzer, Robert M., Andres, Allen M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7237417/
https://ncbi.nlm.nih.gov/pubmed/32427925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64924-2
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