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The zebrafish NLRP3 inflammasome has functional roles in ASC-dependent interleukin-1β maturation and gasdermin E–mediated pyroptosis

The NLR family pyrin domain containing 3 (NLRP3) inflammasome is one of the best-characterized inflammasomes in humans and other mammals. However, knowledge about the NLRP3 inflammasome in nonmammalian species remains limited. Here, we report the molecular and functional identification of an NLRP3 h...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Li, Jiang-Yuan, Wang, Yue-Yi, Shao, Tong, Fan, Dong-Dong, Lin, Ai-Fu, Xiang, Li-Xin, Shao, Jian-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983845/
https://ncbi.nlm.nih.gov/pubmed/31852739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011751
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