Propofol directly induces caspase-1-dependent macrophage pyroptosis through the NLRP3-ASC inflammasome

Propofol infusion syndrome (PRIS) is an uncommon life-threatening complication observed most often in patients receiving high-dose propofol. High-dose propofol treatment with a prolonged duration can damage the immune system. However, the associated molecular mechanisms remain unclear. An increasing...

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發表在:Cell Death Dis
Main Authors: Sun, Lingbin, Ma, Wei, Gao, Wenli, Xing, Yanmei, Chen, Lixin, Xia, Zhengyuan, Zhang, Zhongjun, Dai, Zhongliang
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637184/
https://ncbi.nlm.nih.gov/pubmed/31316052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1761-4
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