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DNase γ-dependent DNA fragmentation causes karyolysis in necrotic hepatocyte

Karyolysis is the complete dissolution of nuclear components of a dying cell. However, the generation mechanism has not been clarified. We studied a necrotic DNA fragmentation factor DNase γ (also known as DNase1L3) and previously found that karyolysis was inhibited in DNase γ deficient (DNase γ(−/−...

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Bibliographische Detailangaben
Veröffentlicht in:J Vet Med Sci
Hauptverfasser: TAKADA, Shuhei, WATANABE, Taiki, MIZUTA, Ryushin
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Japanese Society of Veterinary Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6983664/
https://ncbi.nlm.nih.gov/pubmed/31735730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.19-0499
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