Modifying ICCA with Trp-Phe-Phe to Enhance in vivo Activity and Form Nano-Medicine

BACKGROUND: 1-(4-isopropylphenyl)-β-carboline-3-carboxylic acid (ICCA) was modified by Trp-Phe-Phe to form 1-(4-isopropylphenyl)-β-carboline-3-carbonyl-Trp-Phe-Phe (ICCA-WFF). PURPOSE: The object of preparing ICCA-WFF was to enhance the in vivo efficacy of ICCA, to explore the possible targeting act...

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發表在:Int J Nanomedicine
Main Authors: Zhang, Xiaoyi, Zhang, Yixin, Wang, Yaonan, Wu, Jianhui, Chen, Haiyan, Zhao, Ming, Peng, Shiqi
格式: Artigo
語言:Inglês
出版: Dove 2020
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982437/
https://ncbi.nlm.nih.gov/pubmed/32021191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S229856
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