BCESA: a nano-scaled intercalator capable of targeting tumor tissue and releasing anti-tumoral β-carboline-3-carboxylic acid

Background: In the discovery of DNA intercalators, β-carbolines compose one member of the most interesting alkaloid family and are of clinical importance. In the efforts, N-(3-benzyloxycarbonyl-β-carboline-1-yl)ethyl-Ser-Ala-OBzl (BCESA) was designed as a nano-scaled DNA intercalator without Dox-lik...

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Enregistré dans:
Détails bibliographiques
Publié dans:Int J Nanomedicine
Auteurs principaux: Wu, Jianhui, Cui, Yue, Zhang, Xiaoyi, Gui, Lin, Wang, Yaonan, Peng, Shiqi, Zhao, Ming
Format: Artigo
Langue:Inglês
Publié: Dove 2019
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508158/
https://ncbi.nlm.nih.gov/pubmed/31118620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S187600
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