Modifying ICCA with Trp-Phe-Phe to Enhance in vivo Activity and Form Nano-Medicine

BACKGROUND: 1-(4-isopropylphenyl)-β-carboline-3-carboxylic acid (ICCA) was modified by Trp-Phe-Phe to form 1-(4-isopropylphenyl)-β-carboline-3-carbonyl-Trp-Phe-Phe (ICCA-WFF). PURPOSE: The object of preparing ICCA-WFF was to enhance the in vivo efficacy of ICCA, to explore the possible targeting act...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Zhang, Xiaoyi, Zhang, Yixin, Wang, Yaonan, Wu, Jianhui, Chen, Haiyan, Zhao, Ming, Peng, Shiqi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2020
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6982437/
https://ncbi.nlm.nih.gov/pubmed/32021191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S229856
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