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Theoretical analyses and experimental validation of the effects caused by the fluorinated substituent modification of DNA
Halogen-modified nucleic acid molecules, such as trifluorothymidine (FTD) and 5-fluorouracil, are widely used in medical science and clinical site. These compounds have a very similar nucleobase structure. It is reported that both of these compounds could be incorporated into DNA. The incorporation...
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| Vydáno v: | Sci Rep |
|---|---|
| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6981298/ https://ncbi.nlm.nih.gov/pubmed/31980685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57899-7 |
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