Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation

Somatic hypermutation (SHM) introduces point mutations into immunoglobulin (Ig) genes but also causes mutations in other parts of the genome. We have used lentiviral SHM reporter vectors to identify regions of the genome that are susceptible (“hot”) and resistant (“cold”) to SHM, revealing that SHM...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Senigl, Filip, Maman, Yaakov, Dinesh, Ravi K., Alinikula, Jukka, Seth, Rashu B., Pecnova, Lubomira, Omer, Arina D., Rao, Suhas S.P., Weisz, David, Buerstedde, Jean-Marie, Aiden, Erez Lieberman, Casellas, Rafael, Hejnar, Jiri, Schatz, David G.
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980758/
https://ncbi.nlm.nih.gov/pubmed/31851922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.039
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料