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Embracing study heterogeneity for finding genetic interactions in large-scale research consortia

Genetic interactions have been recognized as a potentially important contributor to the heritability of complex diseases. Nevertheless, due to small effect sizes and stringent multiple-testing correction, identifying genetic interactions in complex diseases is particularly challenging. To address th...

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Опубликовано в: :Genet Epidemiol
Главные авторы: Liu, Yulun, Huang, Jing, Urbanowicz, Ryan J., Chen, Kun, Manduchi, Elisabetta, Greene, Casey S., Moore, Jason H., Scheet, Paul, Chen, Yong
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6980207/
https://ncbi.nlm.nih.gov/pubmed/31583758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.22262
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