Large-scale replication and heterogeneity in Parkinson disease genetic loci

OBJECTIVE: Eleven genetic loci have reached genome-wide significance in a recent meta-analysis of genome-wide association studies in Parkinson disease (PD) based on populations of Caucasian descent. The extent to which these genetic effects are consistent across different populations is unknown. MET...

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Main Authors: Sharma, Manu, Ioannidis, John P.A., Aasly, Jan O., Annesi, Grazia, Brice, Alexis, Van Broeckhoven, Christine, Bertram, Lars, Bozi, Maria, Crosiers, David, Clarke, Carl, Facheris, Maurizio, Farrer, Matthew, Garraux, Gaetan, Gispert, Suzana, Auburger, Georg, Vilariño-Güell, Carles, Hadjigeorgiou, Georgios M., Hicks, Andrew A., Hattori, Nobutaka, Jeon, Beom, Lesage, Suzanne, Lill, Christina M., Lin, Juei-Jueng, Lynch, Timothy, Lichtner, Peter, Lang, Anthony E., Mok, Vincent, Jasinska-Myga, Barbara, Mellick, George D., Morrison, Karen E., Opala, Grzegorz, Pramstaller, Peter P., Pichler, Irene, Park, Sung Sup, Quattrone, Aldo, Rogaeva, Ekaterina, Ross, Owen A., Stefanis, Leonidas, Stockton, Joanne D., Satake, Wataru, Silburn, Peter A., Theuns, Jessie, Tan, Eng-King, Toda, Tatsushi, Tomiyama, Hiroyuki, Uitti, Ryan J., Wirdefeldt, Karin, Wszolek, Zbigniew, Xiromerisiou, Georgia, Yueh, Kuo-Chu, Zhao, Yi, Gasser, Thomas, Maraganore, Demetrius, Krüger, Rejko
Format: Artigo
Sprog:Inglês
Udgivet: Lippincott Williams & Wilkins 2012
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414661/
https://ncbi.nlm.nih.gov/pubmed/22786590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318264e353
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