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Linkage Disequilibrium-Based Quality Control for Large-Scale Genetic Studies
Quality control (QC) is a critical step in large-scale studies of genetic variation. While, on average, high-throughput single nucleotide polymorphism (SNP) genotyping assays are now very accurate, the errors that remain tend to cluster into a small percentage of “problem” SNPs, which exhibit unusua...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2475504/ https://ncbi.nlm.nih.gov/pubmed/18670630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000147 |
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