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Accounting for Decay of Linkage Disequilibrium in Haplotype Inference and Missing-Data Imputation

Although many algorithms exist for estimating haplotypes from genotype data, none of them take full account of both the decay of linkage disequilibrium (LD) with distance and the order and spacing of genotyped markers. Here, we describe an algorithm that does take these factors into account, using a...

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Библиографические подробности
Главные авторы: Stephens, Matthew, Scheet, Paul
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society of Human Genetics 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196397/
https://ncbi.nlm.nih.gov/pubmed/15700229
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