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Accounting for Decay of Linkage Disequilibrium in Haplotype Inference and Missing-Data Imputation

Although many algorithms exist for estimating haplotypes from genotype data, none of them take full account of both the decay of linkage disequilibrium (LD) with distance and the order and spacing of genotyped markers. Here, we describe an algorithm that does take these factors into account, using a...

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Detalhes bibliográficos
Main Authors: Stephens, Matthew, Scheet, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196397/
https://ncbi.nlm.nih.gov/pubmed/15700229
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