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Pharmacokinetics and pharmacodynamics of nitric oxide mimetic agents

Drug discovery focusing on NO mimetics has been hamstrung due to its unconventional nature. Central to these challenges is the fact that direct measurement of molecular NO in biological systems is exceedingly difficulty. Hence, drug development of NO mimetics must rely upon measurement of the NO don...

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Detalles Bibliográficos
Publicado en:Nitric Oxide
Main Authors: Horton, Austin, Schiefer, Isaac T.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6979316/
https://ncbi.nlm.nih.gov/pubmed/30641123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2019.01.001
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