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Pharmacokinetics and pharmacodynamics of nitric oxide mimetic agents

Drug discovery focusing on NO mimetics has been hamstrung due to its unconventional nature. Central to these challenges is the fact that direct measurement of molecular NO in biological systems is exceedingly difficulty. Hence, drug development of NO mimetics must rely upon measurement of the NO don...

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Bibliographic Details
Published in:Nitric Oxide
Main Authors: Horton, Austin, Schiefer, Isaac T.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6979316/
https://ncbi.nlm.nih.gov/pubmed/30641123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2019.01.001
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