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Beyond Energy Metabolism: Exploiting the Additional Roles of NAMPT for Cancer Therapy
Tumor cells have increased requirements for NAD(+). Thus, many cancers exhibit an increased reliance on NAD(+) production pathways. This dependence may be exploited therapeutically through pharmacological targeting of NAMPT, the rate-limiting enzyme in the NAD(+) salvage pathway. Despite promising p...
Gorde:
| Argitaratua izan da: | Front Oncol |
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| Egile nagusia: | |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Frontiers Media S.A.
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6978772/ https://ncbi.nlm.nih.gov/pubmed/32010616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01514 |
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