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HGG-33. EXPLOITING METABOLIC DEFECTS WITH NAMPT INHIBITORS IN DIPG

Diffuse intrinsic pontine glioma (DIPG) are universally lethal pediatric brain tumors with limited treatment options. We recently performed synthetic lethal drug screen with a panel of DNA repair and metabolic inhibitors in vitro, in patient-derived DIPG cells and isogenic cell lines engineered to c...

詳細記述

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書誌詳細
出版年:Neuro Oncol
主要な著者: Muraleedharan, Ranjithmenon, Heer, Collin, Sundam, Ranjini, Brenner, Charles
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8168214/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noab090.097
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