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Ganaxolone enhances microglial clearance activity and promotes remyelination in focal demyelination in the corpus callosum of ovariectomized rats

AIM: Experimental studies have shown that the progesterone metabolite, allopregnanolone, is endowed with promyelinating effects. The mechanisms underlying these promyelinating effects are not well understood. Therefore, we explored the impact of allopregnanolone's synthetic analogue, ganaxolone...

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Detaylı Bibliyografya
Yayımlandı:CNS Neurosci Ther
Asıl Yazarlar: Mouihate, Abdeslam, Kalakh, Samah
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6978248/
https://ncbi.nlm.nih.gov/pubmed/31332963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cns.13195
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